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Nucleus

Canine Supplement for Hip & Joints

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Nucleus contains Glucosamine, Sodium Hyaluronate, and MSM (Methylsulfonylmethane). This combination of ingredients helps maintain your dog’s cartilage and connective tissue. Nucleus comes in chewable tablets and is a tasty formula to help keep your pup active.

One in five dogs (20%) experience joint issues in their lifetimes

11270 Reviews
"The best feeling as a pet owner is knowing you've done everything you can for your pet's health. Pupper ensures you'll have that feeling everyday."
Discover Magazine Science Publication

Methylsulfonylmethane Shows A Pattern Of Lower Pain Levels

Methylsulfonylmethane or section is an organic sulfur containing compound that is well known for its joint health benefits. It can be given to both canines and humans.

The graph here shows the results of a study, which was a randomized, double-blind, placebocontrolled trial evaluating the effects of section on oxidative stress, cell damage and pain.

The results showed a pattern of lower pain levels in the section group.Compared to placebo, section supplementation resulted in non-significantly lower muscle pain at T1 (p = 0.063), and lower muscle pain at T2 and T3. The levels of reduction in the section group at T1, T2, and T3 were at levels considered clinically significant (clinical significance defined as Δ > 10 mm) [25, 26], but none reached statistical significance.

Joint pain can be seen in dogs of all breeds and ages.

Developmental joint problems are caused by improper development of the joints while your dog is young, which is often rooted in their genetics, and may result in more serious injuries like hip or elbow dysplasia. These issues are present in your pup from the outset. 

Many dog breeds, particularly large and giant dogs, are predisposed to painful joint issues such as:

  • Rottweilers are prone to developing knee and ankle joint problems
  • Bernese Mountain Dogs commonly develop elbow dysplasia
  • Newfoundlands are one of the breeds that are most prone to developing issues in their cruciate ligament.

If you are purchasing a dog from a breeder, you should consider asking them about any predispositions their breed or lineage might have to joint issues. A good breeder will provide you with that information unprompted, but it never hurts to ask if you don't receive it.

Target Joint Problems With Complete Joint Support

Nucleus has 8 active ingredients and 14 inactive ingredients, all working in harmony to target hip and joint problems for your pup.

  • Glucosamine for dogs can help relieve pain, stiffness and discomfort in joints by speeding up your dog's natural healing process and stimulating cartilage growth.
  • Hyaluronic Acid belongs to a class of molecules called glycosaminoglycans, which are highly polar which means they attract water and bind with it creating natural shock absorption and lubrication of joints.
  • Methylsulfonylmethane is a joint healer for its ability to reduce inflammation, block pain signals and help strengthen the structural bond of connective tissue.

Our Mission: Backed By Science

Your canine's health can be incredibly complex and difficult to understand. Our goal is to arm dog owners with the necessary information they need to make the best decision for their pups.

We believe that good products starts with good ingredients. Every step of the supply chain have been vetted. Nucleus was formulated with high quality ingredients from our partner farmer and vendors. Your pup deserves the best.

Nucleus was formulated for maximum effectiveness and absorption. All products are tested for purity and quality from third party laboratories.

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Pure Ingredients From The Earth.

Our products are made from the highest quality and purest ingredients. No fillers. No bad stuff. No corners cut. Only the good stuff.

  • Active Ingredients
    Glucosamine, MSM, Green Lippe Mussel, Boswellia, Turmeric (95% Curcuminoid), Chondroitin, Sodium Hyaluronate, Undenatured Collagen type II.
  • Inactive Ingredients
    Ascorbic Acid, Calcium Propionate, Coconut Flour, Flax Oil, Gelatin, Ginger, Glycerin, Mixed Tocopherols, Rosemary Extract, Sorbic Acid, Sunflower Lecithin, Tapioca Flour, Turkey Powder, Water.

Return Policy

A full refund is available for all UNOPENED products. All you have to do is ship the products back within 30 days of your purchase. A shipping label is provided for returns upon request.

    Frequently Asked Questions

  • How do subscriptions work?
    Our subscription plans are our most cost effective option. You get 20% off of your order and you can adjust the renewal timeframe at your whim. Want to skip a shipment? Easy, just click a few buttons. Want our products to be delievered every 2 weeks? Every 2 months? Every third of the month? We've got you.
  • How much is one serving?
    Dogs 25 lbs and under may take 1 chew and dogs over 25 lbs may take 2.
  • How long do you take to ship?
    For domestic orders, we take 1-2 days to process orders, then another 3-5 days for shipping. For international orders, we take 1-2 days to process and up to 2 weeks for shipping depending on where you are located.
  • Who do you ship with?
    We primarily use USPS or UPS, depending on your location.
  • Can I combine your supplements with other supplements?
    While our supplements are safe and can usually be used with other supplements, we still encourage you to consult a veterinarian. Our supplements can be combined with each other. Please follow the dosage instructions for each specific supplement.
  • Are your ingredients natural?
    Yes, our ingredients are all-natural. We believe that the best ingredients were grown or raised with the best practices. We actively vett our supply chain to ensure that our farmers, suppliers, and vendors all work within the confines of what we call "just".
  • Can I buy your products in stores?
    All Pupper products can be purchased directly from our website and are not currently available in any retail stores. We can ship anywhere in the world.

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Fuel was formulated for optimal health and peak performance using all-natural ingredients. Free-range chicken, real veggies, all-natural ingredients packed full of nutrients. We recommend replacing 20% of your dog's food with our topper for maximum results.

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A special blend of botanicals, oils, and ingredients that conditions, moisturizes, and soothes your pup's skin and coat. Restores a silky feel to the coat and helps improve dry and wet combing.

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Our toothpaste formulated specifically for canines. Designed to naturally freshen their breath and to cleanse their teeth and gums. We use botanical extract and oils to naturally freshen your pup's breath and to help remove plaque and tartar.

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Make Nucleus a part of your pups routine for an active future.

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